In the world of industrial cooling, glycol chillers are the backbone of temperature control for breweries, wineries, distilleries, and other process-driven operations. While these systems are designed for continuous use, there are strategic reasons why extended shutdowns can be beneficial, especially during seasonal lulls or planned maintenance windows. The article covers preventative maintenance, energy and cost savings, system upgrades, sustainability considerations, operational planning, glycol degradation prevention, and refrigerant migration risks, concluding with guidance for safe shutdown procedures.